- The Department of Nuclear Physics has a history of development closely associated with the Faculty of Physics and Engineering Physics at the University of Science, VNUHCM. The department was established in 1965 under the name "Atomic Department". Subsequently, its name was changed to the Department of Nuclear Physics, which oversees the Nuclear Engineering and Medical Physics programs, and is part of the Faculty of Physics and Engineering Physics, University of Science, VNUHCM. The current Head of the Department is Assoc. Prof. Dr. Trần Thiện Thanh.
- The Nuclear Engineering Program was established in 2011 and had its first academic enrollment in 2012. The purpose of the program is to train nuclear human resources to meet the growing societal demand for nuclear applications in fields such as industry and agriculture.
- The Medical Physics Program was established and had its first academic enrollment in 2020. The purpose of the program is to train human resources with professional qualifications in the application of modern physics technology and techniques for disease diagnosis and treatment, particularly in cancer therapy.
The department's personnel consists of 20 permanent faculty members, including 01 Professor (Prof. Dr.), 04 Associate Professors (Assoc. Prof. Dr.), 08 Doctors (Dr.), 06 PhD candidates, and 01 Master of Science (MSc.).