FACULTY OF PHYSICS & ENGINEERING PHYSICS

DEPARTMENT OF NUCLEAR PHYSICS - NUCLEAR ENGINEERING - MEDICAL PHYSICS

Investigation of the effects of chemotherapy on trace element contents in the nails in patients with colorectal cancer

Phuong Truc Huynh, Binh Thanh Dinh, Linh Thi Truc Nguyen, Loan Thi Hong Truong, Hanh Van Nguyen, Dung Manh Ho, Dong Van Nguyen, Anh Tuan Tran

Journal of Radioanalytical and Nuclear Chemistry (2021) 328:1173–1180

Abstract:

The aim of this study was to evaluate the effects of cancer treatment with chemotherapy for the trace elements in nails of patients with colorectal cancer. The contents of trace elements in the nails of 102 patients with colorectal cancer (including treated and untreated) and 60 healthy subjects were analyzed using k0-standardization method of neutron activation analysis. All participants aged between 32 and 76. Result of this study showed that the contents of nine trace elements (As, Br, Co, Cr, Hg, Fe, Sc, Se, and Zn) in the nails were measured. Furthermore, this study showed that there was significant difference in the contents of the elements Fe, Se, and Zn in both colon and rectal cancer patient groups between untreated and treated subjects with chemotherapy. We conclude that the contents of Fe, Se, and Zn in the nail samples may be used to evaluate of the colorectal cancer risk, and they may be affected by chemotherapy.

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Investigation of prompt 𝛾-ray neutron activation spectrometer at the Dalat research reactor using Geant4 simulation

Chau Thanh Tai, Tran Thien Thanh, Pham Ngoc Son, Chau Van Tao

Radiation Physics and Chemistry 208 (2023) 110884

Abstract:

The prompt 𝛾-ray activation analysis (PGAA) detector, which has been developed at the Dalat nuclear research reactor, is investigated in this study. The Geant4 model is proposed for the PGAA detector to evaluate the Compton scattering background suppression. Based on this model, the detector efficiency in the energy range from 0.1 MeV to 11 MeV was determined using the thermal neutron capture of chlorine, titanium, nitrogen, and reference sources. The detector efficiencies in the unsuppressed and suppressed modes and the difference of efficiencies in both modes were calculated. Additionally, the suppression of additional peaks of the PGAA detector was also estimated in this work. Finally, the polynomial function for the detector efficiency and the ratio of additional peaks to corresponding full-energy peaks were determined. This work makes an essential contribution to the analysis of prompt 𝛾-ray spectrum acquired from the PGAA detector at the Dalat nuclear research reactor.

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Investigating the Radiation Shielding Properties of Iron Oxide-enhanced Heavy Concrete through Gamma Transmission Method

Le Hoang Minh, Dang Van Hau, Nguyen Duy Khai, Phan Nguyen Hoang Long, Tran Thi My Duyen, Nguyen Thi Truc Linh, Huynh Dinh Chuong, Tran Thien Thanh

IEEJ Transactions on Sensors and Micromachines

Abstract:

This study investigates the radiation shielding properties of construction materials, with a focus on iron oxide (Fe2O3)-enhanced heavy concrete. It covers a range of Fe2O3 concentrations from 0% to 12.9% in concrete formulations and uses M200-grade standard samples as references. The study observes a linear increase in sample density as Fe2O3 content rises. A gamma transmission measurement system utilizing NaI(Tl) detectors assesses shielding effectiveness. It measures linear attenuation coefficients for concrete samples at 59.54 keV (241Am), 661.7 keV (137Cs), and 1332 keV (60Co) energy levels. Precise measurements result from careful calibration of detectors and radiation sources, ensuring a focused gamma ray beam. The findings establish a direct correlation between linear attenuation coefficients and Fe2O3 content at each energy level. Notably, samples with the highest Fe2O3 concentration exhibit significant increases in attenuation coefficients, such as 19.6% (59.54 keV), 7.75% (661.7 keV), and 13.5% (1332 keV), compared to standard samples. These insights suggest the potential use of iron oxide-enhanced heavy concrete as effective radiation shielding in construction applications.

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Influences of Soil and Plant Types on The Mitigation Rateof Radium‑226 in The Cultivated Soils

Van Thang Nguyen, Nguyen Phong Thu Huynh,  Cong Hao Le

Water Air Soil Pollut (2024) 235:95

Abstract

The effects of fertilizers, irrigation water, and air dust pollution on the long-term accumulation of radionuclides in surface soils have been investigated worldwide. In addition, many factors cause the removal of radionuclides from the soil. The removal rate is difficult to estimate because it is controlled by several parameters such as agricultural practices and soil properties. In this study, the mitigation rate of Ra-226 in the topsoil of agricultural soils in 20 fields in Vietnam was measured. The rate was considered two main processes that rejected radionuclides from the topsoil. Moreover, the soil-to-plant transfer factors (TF) and solid/liquid partition coefficients (Kd) for these soils have been reported. It was found that the obtained values of TF and Kd were wide and depended on the plant and soil types. The new experimental method gives the leaching rate of Ra-226 matching that based on the models, except for the rice paddy soil. For twenty considered soils, the mitigation rates of Ra-226 were from 0.1 to 0.58 Bq kg−2 y−1. The trend of Ra-226 mitigation correlated with the uptake ability of the plant (TF) and the Ra-226 concentration in pore water (Kd).

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Truong Thi Hong Loan, Vu Ngoc Ba, Dang Thi Thuy Dan, Vuong Minh Tri, Huynh Thi Yen Hong, Truong Huu Ngan Thy, Nguyen Thi Truc Linh, Le Cong Hao & Huynh Truc Phuong 

Journal of Radioanalytical and Nuclear Chemistry 327, 609-616(2021)

Abstract:

In this work, the impacts of TENORM (Technologically Enhanced Naturally Occurring Radioactive Materials) from fertilizers on soil and vegetables were estimated. We investigated both the activity concentration of the natural radionuclides and the annual effective dose rate due to the ingestion of vegetables in the crops using fertilizers at the agricultural zone of Hoc Mon, Ho Chi Minh City, Vietnam. The results show that there have not yet been signs of radioactive residues from using conventional fertilizers in agricultural land after a crop at the surveyed area and time. The radiological impact of surveyed vegetables was negligible to the public health.

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Impact of Nonlocality Effects in Proton Optical Potential from Folding Model on p+ 16O Elastic Scattering at Low Energies

Nguyen Hoang Phuc, Nguyen Tri Toan Phuc & Do Cong Cuong 

Braz J Phys 54, 226 (2024)

Abstract:

We employ the single folding model to calculate the optical potential (OP) for the p+16O scattering system, in which the exchange term of the OP is nonlocal. In most studies, this term is approximated to a local form to simplify the calculations. In this work, the folding OP, including the nonlocal exchange term, is constructed based on the CDM3Y3 effective nucleon-nucleon (NN) interaction. The Schrödinger equation for the nucleon-nucleus scattering with the nonlocal OP is solved exactly using the Lagrange-mesh R-matrix method. By comparing the scattering cross sections calculated with the nonlocal potential and the localized approximation, we can assess the impact of the nonlocality effects in proton-nucleus elastic scattering. The calculated results demonstrate that the nonlocality effect of the OP significantly influences the low-energy elastic scattering cross sections of p+16O .

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